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(creator)"]},{"label":"Administrative Note","value":"Node ID: 17108<br>Administrative Notes: <p>Old URL: https://wesscholar.wesleyan.edu/etd_mas_theses/231</p>_x000D_<br>Author Contact: elliot.james.williams@gmail.com<br>Local Identifier: 231_williams_ej_thesis<br>PID: ir:2587"},{"label":"Degree","value":["Master of Arts"]},{"label":"Description","value":"<p>The ribosome is a biological machine which translates mRNA into protein, at the rate of one amino acid from a decoded codon every tenth of a second. Computational chemists have developed a technique called Molecular Dynamics (MD), which allows molecular behaviour to be explicitly modeled and calculated on the nanosecond timescale using computers.</p>_x000D_\n_x000D_\n<p>For my thesis, I used the AMBER MD framework to model the ribosome’s catalytically active core, to evaluate the feasibility of potential mRNA-rRNA interaction during ribosomal translocation. 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