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Emerging research suggests that negative symptoms in schizophrenia can be divided into two primary domains of deficits: expressive (e.g. alogia, blunted affect) and experiential (e.g. avolition, anhedonia, asociality) (Harvey et al., 2017; Kirkpatrick & Fischer, 2006; Liemburg et al., 2013). These domains are hypothesized to be neurobiologically distinct (Galderisi et al., 2015), often with different functional consequences. Cognitive remediation, a behavioral intervention involving repeated task practice and strategy coaching, is known for its efficacy in improving neurocognitive and related functional deficits in schizophrenia, but treatment outcomes vary significantly among patients (Barlati et al., 2019; Lejeune et al., 2021; Medalia, 2005; Wykes et al., 2011). Research continues to point to relationships between negative symptoms and functional outcomes (Llerena et al., 2018; Marder & Galderisi, 2017; Marder & Umbricht, 2023). Expansion upon this association suggests that experiential deficits may be a stronger predictor of functional outcomes in schizophrenia as compared to expressive deficits (Glenthøj et al., 2020; Harvey et al., 2017; Okada et al., 2020), raising the possibility that this relationship may extend to cognitive remediation outcomes. In a sample of 110 participants diagnosed with schizophrenia or schizoaffective disorder, this study aimed to test the hypotheses that: (1) experiential and expressive negative symptoms constitute separate classes of symptoms, and (2) that these two domains differentially predict cognitive and functional improvement by cognitive remediation. The Positive and Negative Syndrome Scale (PANSS) was used for negative symptom assessment and measures assessing cognitive remediation outcomes covered attention, verbal episodic memory, working memory, language ability, and adaptive function for everyday life. Results supported prior work that the expressive and experiential negative symptoms are distinct constructs, but were inconsistent with hypotheses that the predictive nature of negative symptom domains is generalizable to cognitive remediation outcomes. Findings suggest that while the distinction between expressive and experiential domains may positively inform clinical evaluation and treatment, other predictors of response to cognitive treatment should be investigated.</p>"},{"label":"Digital Identifier","value":"b2026-koganspivack"},{"label":"Digital Object Identifier (DOI)","value":"https://doi.org/10.14418/a89umkwc"},{"label":"Digital Origin","value":["born digital"]},{"label":"Discipline","value":["Neuroscience & Behavior"]},{"label":"Date","value":"April 15, 2026"},{"label":"EDTF Date","value":"D:00 M:00 Y:2026"},{"label":"File Format","value":["application/pdf"]},{"label":"Genre","value":["theses"]},{"label":"Group","value":["Theses & Dissertations"]},{"label":"Held By","value":"Wesleyan University Library, Wesleyan University, Middletown, CT, USA"},{"label":"Language","value":["English"]},{"label":"Repository","value":["University Archives"]},{"label":"Rights","value":["In Copyright"]},{"label":"Thesis 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