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We sought to determine if changing the animal’s gut microbiome via bacterial exposure to the strain Pseudomonas mendocina, MSPm1, would yield similar behavioral changes. Sensory integration is a complex behavior that requires the collaborative efforts of the receptor DAF-2 and the insulin-like peptide INS-31. Animals exposed to MSPm1 overwhelmingly behave in a parallel manner to food deprived animals, despite MSPm1 being a viable food source for the model organism. Specifically, animals exposed to MSPm1 exhibit high chemotactic behavior after short periods of exposure compared to animals not exposed to any bacterial strains. MSPm1 exposure also induces a metabolic shift in an ins-31-dependent manner, while independent of fat metabolism. Using an aldicarb assay, we observe that MSPm1-exposed animals have higher rates of synaptic transmission than non-exposed animals. Altogether, our study shows how exposure to MSPm1 alters risk-taking behavior, delineating the specific intestine-neuron signaling pathways involved."},{"label":"Publication Information","value":"BIO 499: Senior Thesis\nCopyright for this work is retained by the author"},{"label":"Faculty Advisor","value":["Dr. Ryan Kenton","Dr. Molly Matty"]},{"label":"College & School","value":["College of Arts and Sciences"]},{"label":"Department","value":["Biology"]},{"label":"Is Part Of","value":["Office of Undergraduate Scholarly Engagement"]},{"label":"Document Type","value":["Honors project"]},{"label":"Undergraduate Collection","value":["Biology Student Works"]}],"description":"Bacterial signaling and mechanisms alter risk-taking behaviors in Caenorhabditis\nelegans","sequences":[{"@type":"sc:Sequence","canvases":[{"@id":"https://iiif.quartexcollections.com/portland/iiif/4239c806-be70-498e-ab00-2de3e4076813/canvas/_1","@type":"sc:Canvas","label":"Savas, Lauren 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